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Canneberge / Cystite

Le 11/05/2015

Etude randomisée, en double-aveugle, contrôlée contre placebo et en cross-over : 12 volontaires sains ont consommé une boisson à base d’extrait de canneberge ou un jus de fruit de canneberge considéré comme le placebo. Après 1 seule prise, des prélèvements sanguins et urinaires ont mis en évidence une augmentation de l'activité anti-oxydante et une inhibition de l'adhésion des bactéries par rapport au placebo.
Mathison BD et al. Consumption of cranberry beverage improved endogenous antioxidant status and protected against bacteria adhesion in healthy humans: a randomized controlled trial. Nutr Res34(5):420-7, 2014 May

Consumption of polyphenol-rich foods is associated with lower risk from many chronic diseases. We hypothesized that a single dose of cranberry beverage would improve indices of oxidative stress, inflammation, and urinary antibacterial adhesion activity in healthy humans. Six males and 6 females (18-35 years; body mass index, 19-25 kg/m(2)) consumed placebo, cranberry leaf extract beverage, or low-calorie cranberry juice cocktail (LCJC) once in a randomized, double-blind, placebo-controlled cross-over experimental design trial. The washout period between beverages was 1 week. Blood was collected 0, 2, 4, 8, and 24 hours after beverage consumption for measuring oxidative and inflammatory biomarkers. Urine was collected at 0, 0 to 3, 3 to 6, 6 to 9, 9 to 12, and 24 hours postintervention to assess antibacterial adhesion activity. Consumption of cranberry leaf extract beverage elevated (p<0.05) blood glutathione peroxidase activity, whereas LCJC consumption increased (p<0.05) glutathione concentrations and superoxide dismutase activity compared with placebo. Cranberry leaf extract beverage and LCJC consumption had no effect on the inflammatory biomarkers measured as compared with placebo. At 0 to 3 hours postconsumption, urine from participants who consumed cranberry beverages had higher (p<0.05) ex vivo antiadhesion activity against P-fimbriated Escherichia coli compared with placebo. An acute dose of cranberry beverages improved biomarkers of antioxidant status and inhibition of bacterial adhesion in urine.

veille scientifique

Canneberge (Cranberry)

Vaccinium macrocarpon

Canneberge (Cranberry)